There are a few different ways to open a CDR file in Illustrator. The easiest way is to use the CDR Editor, which is located in the Tools palette. To open a CDR file in the editor, click on the CDR icon in the Tools palette and then select Open from the popup menu. Another way to open a CDR file is to use the Cmd+F5 keyboard shortcut, which opens theCDR Editor with your current selection.